Hgf beta chain variants

Details Hgf beta chain variants Hgf beta chain variants

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01)

Patent

CA 2605037

The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using these modulators.

La présente invention concerne des modulateurs HGF/Met qui contiennent du HGF (facteur de croissance des hépatocytes) ayant des mutations dans des régions qui affectent la fonction du HGF, et des antagonistes qui ciblent lesdites régions. Elle concerne en outre des méthodes d'identification, de production et d'utilisation desdits modulateurs.

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