High affinity anti-prostate stem cell antigen (psca)...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 49/16 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2698343

The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA.

La présente invention porte sur de nouveaux anticorps à haute affinité et sur des fragments de ceux-ci qui se lient à l'antigène de cancer PSCA. Les anticorps de la présente invention peuvent être utilisés pour un diagnostic, un pronostic, un traitement, une visualisation et analogues, d'un cancer. La présente invention propose également des procédés pour la détection, la visualisation et le traitement de divers cancers exprimant des PSCA.

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