High affinity antibody antagonists of interleukin-13...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 14/715 (2006.01)

Patent

CA 2666679

High affinity antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are effective in the inhibition of IL-13R.alpha.l- mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13R.alpha.l activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13R.alpha.l-mediated activities are also disclosed.

L'invention concerne des anticorps antagonistes de haute affinité dirigés contre le récepteur alpha 1 humain de l'interleukine-13. Ces molécules d'anticorps inhibent efficacement les activités dont la médiation est assurée par IL-13R.alpha.1, et constituent par conséquent d'excellents antagonistes pouvant être utilisés pour traiter des états associés à l'activité de hIL-13R.alpha.1. La présente invention concerne également un acide nucléique codant ces molécules d'anticorps, des vecteurs et des cellules hôtes, ainsi que des compositions comportant lesdites molécules d'anticorps. Cette invention se rapporte en outre à des procédés d'utilisation des molécules d'anticorps pour inhiber ou exercer une action contre les activités dont la médiation est assurée par IL-13R.alpha.1.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

High affinity antibody antagonists of interleukin-13... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High affinity antibody antagonists of interleukin-13..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High affinity antibody antagonists of interleukin-13... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1756120

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.