High affinity binding site of hgfr and methods for...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/28 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) C07K 14/71 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2665958

Use of a polynucleotide encoding or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor.

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