C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2652886
The present invention relates to recombinant human or humanized polypeptides which bind to .alpha.5.beta.1 integrin with high affinity and blocking function. Further, diagnostic and pharmaceutic applications of the polypeptides are disclosed.
La présente invention concerne des polypeptides recombinants humains ou humanisés qui se lient à l'intégrine .alpha.5.beta.1 avec une affinité élevée et qui ont une fonction de blocage. L'invention concerne en outre des applications diagnostiques et pharmaceutiques des polypeptides.
Bosslet Klaus
Menrad Andreas
Petit-Frere Corinne
Petrul Heike
Prassler Josef
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
Morphosys Ag
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