C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07K 14/745 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) C07B 61/00 (2006.01)
Patent
CA 2320100
Methods are described for the identification and preparation of high-affinity Nucleic Acid Ligands to Complement System Proteins. Methods are described for the identification and preparation of high affinity Nucleic Acid Ligands to Complement System Proteins C1q, C3 and C5. Included in the invention are specific RNA ligands to C1q, C3 and C5 identified by the SELEX method.
L'invention concerne des procédés d'identification et de préparation de ligands à forte affinité d'acides nucléiques de protéines du système complémentaire. Ces procédés consistent à identifier et préparer des ligands à forte affinité d'acides nucléiques des protéines C1q, C3 et C5 du système complémentaire. L'invention concerne également des ligands d'ARN spécifiques des protéines C1q, C3 et C5, identifiés selon le processus SELEX.
Biesecker Gregory
Gold Larry
Gilead Sciences Inc.
Mbm Intellectual Property Law Llp
Nexstar Pharmaceuticals Inc.
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