High affinity nucleic acid ligands of complement system...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/00 (2006.01) A61K 31/7088 (2006.01) C07H 21/02 (2006.01) C12N 15/11 (2006.01) C40B 30/04 (2006.01)

Patent

CA 2243578

Methods are described for the identification and preparation of high affinity nucleic acid ligands to Complement System Proteins. Methods are described for the identification and preparation of high affinity nucleic acid ligands to Complement System Protein, C1q. Included in the invention are specific RNA ligands to C1q identified by the SELEX method.

Procédés d'identification et de préparation d'acides nucléiques ligands à forte affinité pour les protéines du système complémentaire. On décrit des méthodes d'identification et de préparation d'acides nucléiques ligands à forte affinité pour la protéine de système complément, C1q. L'invention concerne également des ligands d'ARN spécifiques à C1q identifiés par la méthode SELEX.

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