High concentration homogenized collagen compositions

Details High concentration homogenized collagen compositions High concentration homogenized collagen compositions

A - Human Necessities

61

K

A61K 38/39 (2006.01) A61K 8/65 (2006.01) A61L 27/24 (2006.01) C08L 89/06 (2006.01) A61K 7/48 (1990.01)

Patent

CA 2128504

High concentration collagen compositions having improved persistence when administered for soft tissue augmentation are prepared from both cross-linked and non-cross-linked collagen starting materials. Suspensions of the starting materials are subjected to vigorous mechanical disruption to reduce the average collagen fiber size to below a threshold level which enhances the injectability of the composition. Thus, both enhanced injectability and enhanced persistence may be achieved using the same formulations.

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