High concentration topical insecticide

A - Human Necessities – 01 – N

Patent

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A01N 43/08 (2006.01) A01N 25/32 (2006.01) A01N 51/00 (2006.01)

Patent

CA 2498181

A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. In one preferred embodiment of the invention, the active ingredient of the insecticide formulation is an amine derivative, having a nitro-methylene group, a nitroamino group or a cyanoamino group, which can be formulated to have low toxicity and excellent insecticidal activity. One particularly suitable insecticide is 1-{(tetrahydro-3-furanyl)methyl}-2-nitro-3- methylguanidine (dinotefuran), an aldulticide that will kill adult fleas, dissolved in phenyl methanol or ethanol and ethyl lactate.

L'invention concerne un insecticide topique pouvant être utilisé en toute sécurité, permettant d'éviter de nombreux effets secondaires nocifs communs aux insecticides topiques classiques. Dans un mode de réalisation préféré de l'invention, le principe actif de la formulation d'insecticide est un dérivé amine, présentant un groupe nitro-méthylène, un groupe nitroamine ou un groupe cyanoamine, pouvant être formulé pour présenter une faible toxicité et une excellente activité insecticide. Un insecticide particulièrement approprié est le 1-{(tétrahydro-3-furanyl)méthyl}-2-nitro-3-méthylguanidine (dinotéfurane), un imagocide permettant de tuer les puces adultes, lequel insecticide étant dissous dans du phényle méthanol ou dans de l'éthanol et dans de l'éthyle lactate.

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