High density fibrous polymers suitable for implant

A - Human Necessities – 61 – L

Patent

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Details

A61L 26/00 (2006.01) A61L 27/24 (2006.01) A61L 27/46 (2006.01) A61L 27/52 (2006.01) C08H 1/06 (2006.01) C08L 89/06 (2006.01)

Patent

CA 2532829

This invention includes malleable, biodegradable, fibrous compositions for application to a tissue site in order to promote or facilitate new tissue growth. One aspect of this invention is a fibrous component that provides unique mechanical and physical properties. The invention may be created by providing a vessel containing a slurry, said slurry comprising a plurality of natural or synthetic polymer fibers and at least one suspension fluid, wherein the polymer fibers are substantially evenly dispersed and randomly oriented throughout the volume of the suspension fluid; applying a force, e.g., centrifugal, to said vessel containing said slurry, whereupon said force serves to cause said polymer fibers to migrate through the suspension fluid and amass at a furthest extent of the vessel, forming a polymer material, with said polymer material comprising polymer fibers of sufficient length and sufficiently viscous, interlaced, or interlocked to retard dissociation of said polymer fibers.

La présente invention se rapporte à des compositions fibreuses malléables et biodégradables, destinées à être appliquées sur une site tissulaire afin de favoriser ou de faciliter la croissance de nouveaux tissus. Un aspect de la présente invention concerne un composant fibreux qui possède des propriétés mécaniques et physiques uniques. Un procédé permettant de produire les compositions selon l'invention consiste : à fournir un récipient contenant une pâte, ladite pâte renfermant une pluralité de fibres polymères naturelles ou synthétiques et au moins un fluide de suspension, lesdites fibres polymères étant dispersées de manière sensiblement uniforme et orientées aléatoirement dans le volume du fluide de suspension ; à appliquer une force, par exemple une force centrifuge, au récipient contenant la pâte, ladite force provoquant la migration desdites fibres polymères à travers le fluide de suspension et leur accumulation sur le bord du récipient, ce qui forme un matériau polymère, ledit matériau polymère contenant des fibres polymères suffisamment longues, visqueuses, et entrelacées ou entrecroisées, pour retarder la dissociation desdites fibres polymères.

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