High-density lipoprotein assay device and method

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/60 (2006.01) C12M 1/34 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/558 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2473244

An assay device and method for measuring the concentration of HDL-associated cholesterol in a blood-fluid sample are described. The assay design is such that removal of non-HDL lipoproteins from a sample and assay of HDL cholesterol in the sample occur without interruption of the assay. The device also prevents interference by reagents used for the HDL assay with other assays carried out on the same sample.

L'invention concerne un procédé et un dispositif de dosage permettant de mesurer la concentration de cholestérol associé à des lipoprotéines à densité élevée (HDL) dans un échantillon de fluide sanguin. Le dosage est conçu de sorte que l'élimination des lipoprotéines non HDL d'un échantillon et le dosage du cholestérol HDL dans cet échantillon s'effectue sans interruption dudit dosage. Le dispositif empêche également l'interférence de réactifs utilisés pour doser HDL avec d'autres dosages effectués sur le même échantillon.

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