High efficiency cardiac gene transfer

Details High efficiency cardiac gene transfer High efficiency cardiac gene transfer

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61K 48/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2422078

Methods for the delivery of genes to improve cardiac function including the use of viral vectors, isolation of the heart from systemic circulation, and induction of hypothermia/cardiac arrest are described. The method results in high-level, long-term expression of reporter genes and enhanced cardiac function in hamster models of heart disease.

L'invention concerne des procédés permettant l'apport de gènes en vue d'améliorer la fonction cardiaque, et impliquant notamment l'utilisation de vecteurs viraux, l'isolation du coeur de la circulation systémique, et l'induction de l'hypothermie/l'arrêt cardiaque. Le procédé permet d'obtenir une expression à long terme, de niveau élevé, des gènes rapporteurs et une fonction cardiaque améliorée dans des modèles de maladie de coeur chez le hamster.

Affiliated with

Also associated with

Rating

High efficiency cardiac gene transfer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High efficiency cardiac gene transfer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High efficiency cardiac gene transfer will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1834204