High enantiomeric purity dexanabinol for pharmaceutical...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/82 (2006.01) A61K 9/48 (2006.01) A61K 31/353 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61K 47/44 (2006.01) C07D 311/80 (2006.01)

Patent

CA 2507815

The present invention relates to a synthetic cannabinoid, dexanabinol, of enantiomeric purity in excess of 99.90% or to a pharmaceutically acceptable salt, ester or solvate of said compound. The present invention also relates to pharmaceutical grade composition comprising said compound of high enantiomeric purity, and uses thereof for prevention and treatment of neurological disorders, chronic degenerative diseases, CNS poisoning cognitive impairment, inflammatory diseases or disorders, autoimmune diseases or disorders, pain, emesis, glaucoma and wasting syndromes.

La présente invention a trait à un cannabinoïde synthétique, le dexanabinol de pureté énantiomérique supérieure à 99,90 % ou à un sel, ester ou solvate pharmaceutiquement acceptable dudit composé. La présente invention a également trait à une composition de qualité pharmaceutique comprenant ledit composé de haute pureté énantiomérique, et ses utilisations pour la prévention et le traitement de troubles neurologiques, de maladies dégénératives chroniques, de la détérioration du système nerveux central, de la déficience intellectuelle, des maladies ou troubles inflammatoires, des maladies ou troubles auto-immuns, de la douleur, du vomissement, du glaucome et des syndromes cachectiques.

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