High expression zymomonas promoters

C - Chemistry – Metallurgy – 12 – N

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C12N 15/09 (2006.01)

Patent

CA 2716590

Identified are mutants of the promoter of the Z. mobilis glyceraldehyde-3- phosphate dehydrogenase gene, which direct improved expression levels of operably linked heterologous nucleic acids. These are high expression promoters useful for expression of chimeric genes in Zymomonas, Zymobacter, and other related bacteria.

Sont identifiés des mutants du promoteur du gène Z. mobilis glycéraldéhyde-3-phosphate déhydrogénase, qui orientent des niveaux d'expression améliorée d'acides nucléiques hétérologues fonctionnellement liés. Il s'agit de promoteurs à expression élevée utilisés pour l'expression de gènes chimériques dans Zymomonas, Zymobacter, et d'autres bactéries apparentées.

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