A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 39/385 (2006.01) C07K 16/00 (2006.01) G01N 33/533 (2006.01)
Patent
CA 2235599
A high fluorescence specific immune enhancing factor and methods of its use are described. The factor comprises a malondialdehyde-acetaldehyde adduct which can be detected in the picomolar range. The specific immunoenhancing factor allowing for a shorter time course for the production of antibody and of higher titer antibodies without the need for adjuvant. The factor may further be used as a general fluorescent label for immunological techniques and can be used to visualize protein interactions and to monitor protein purification procedures.
L'invention concerne un facteur de renforcement de l'immunité spécifique, à haute fluorescence, ainsi que ses procédés d'utilisation. Ledit facteur comprend un produit d'addition au malondialdéhyde-acétaldéhyde pouvant être détecté à des niveaux picomolaires. Ce facteur de renforcement de l'immunité spécifique permet de produire plus rapidement des anticorps plus concentrés, sans nécessité de recourir à un adjuvant. On peut aussi l'utiliser de façon générale en guise de marqueur fluorescent servant pour des techniques immunologiques, et pour visualiser des interactions protéiniques et surveiller des procédures de purification de protéines.
Klassen Lynell W.
Mcdonald Thomas L.
Sorrell Michael F.
Thiele Geoffrey M.
Tuma Dean J.
Bereskin & Parr
The Board Of Regents Of The University Of Nebraska
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