High gradient magnetic separation of biological material

C - Chemistry – Metallurgy – 07 – B

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07B 63/00 (2006.01) B03C 1/01 (2006.01) B03C 1/28 (2006.01)

Patent

CA 2698699

The invention relates to a high gradient magnet separation device for the separation or purification of magnetic or magnetically labeled biological material, comprising a magnet (7), a separating column (1), and a ferromagnetic matrix (2) that can be arranged in an interior chamber of the separating column, and a storage container (11) containing a buffer solution for the equilibration of the separating column (1) and/or for the suspension of the biological material, wherein during operation a magnetic field created by the magnet (7) creates a high gradient magnetic field in the matrix (2) and buffer solution can flow from the storage container (11) through the separating column (1). For this purpose, the buffer solution comprises a base solution and macromolecules that can saturate nonspecific binding sites of the matrix (2).

L'invention concerne un dispositif de séparation magnétique à haut gradient de champ pour séparer ou purifier un matériau biologique magnétique ou à marquage magnétique, ce dispositif comportant un aimant (7), une colonne de séparation (1), une matrice ferromagnétique (2) montée dans une cavité de la colonne de séparation, et un réservoir (11) contenant une solution tampon pour l'équilibre de la colonne de séparation (1) et/ou la suspension du matériau biologique. En fonctionnement, un champ magnétique généré par l'aimant (7) peut générer dans la matrice (2) un champ magnétique à haut gradient et la solution tampon peut sortir du réservoir (11) pour traverser la colonne de séparation (1). La solution tampon contient une solution de base et des macromolécules qui peuvent saturer des sites de liaison non spécifiques de la matrice (2).

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

High gradient magnetic separation of biological material does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High gradient magnetic separation of biological material, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High gradient magnetic separation of biological material will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1755181

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.