C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/34 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) C07K 1/22 (2006.01) C07K 14/01 (2006.01) C07K 14/81 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12Q 1/34 (2006.01) C12Q 1/48 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2204914
A process for producing and purifying peptides and for producing peptide/protein antigens for antibody production is described. The process utilizes fusion proteins and specifically fusion proteins in which the fusion protein carrier segment includes an amino acid sequence at least about 65 amino acids long and in which the amino acid sequence does not contain negative or positive charged side chains of amino acids.
L'invention se rapporte à un procédé de production et de purification de peptides et de production d'antigènes peptidiques/protéiniques en vue de produire des anticorps. Le procédé met en oeuvre des protéines de fusion et spécifiquement des protéines de fusion dans lesquelles le segment porteur de protéines de fusion comprend une séquence ayant une longueur d'au moins environ 65 amino acides, cette séquence d'amino acides ne contenant pas de chaînes latérales d'amino acides à charge négative ou positive.
Haak-Frendscho Mary
Knuth Mark W.
Lesley Scott A.
Shultz John W.
Villars Catherine E.
Borden Ladner Gervais Llp
Promega Corporation
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