High level expression of basic fibroblast growth factor...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) C07K 14/50 (2006.01) C12N 1/21 (2006.01) C12N 15/71 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2078875

DNA sequences are provided which encode a form of basic fibroblast growth factor lacking one of the alanine residues im- mediately following the N-terminal methionine residue of the primary translation product. The DNA sequences can be expressed to produce basic fibroblast growth factor having a homogeneous N-terminus.

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