High level expression of functional human plasminogen...

Details High level expression of functional human plasminogen... High level expression of functional human plasminogen...

C - Chemistry, Metallurgy

12

N

530/13, 167/44,

C12N 15/73 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) C12N 1/21 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) G01N 33/86 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2016387

43 BT-0028 Title HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-l) IN E. COLI Abstract Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA.

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