High level expression of human cyclooxygenase-2

Details High level expression of human cyclooxygenase-2 High level expression of human cyclooxygenase-2

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 15/11 (2006.01) C12N 15/86 (2006.01) C12Q 1/26 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2172611

The invention discloses a cDNA consisting of human cyclooxygenase-2 cDNA attached to 3'flanking sequence of human cyclooxygenase-1 methods for increasing the expression of human cyclooxygenase-2 in transformed cells and assays for preferentially and independently measuring cyclogenase-2 in samples.

Cette invention concerne un ADNc constitué d'ADNc cyclooxygénase-2 d'origine humaine qui est attaché à la séquence adjacente 3' de la cyclooxygénase-1 humaine, des procédés permettant d'augmenter l'expression de la cyclooxygénase-2 humaine dans des cellules transformées et des dosages utilisés pour mesurer de manière préférentielle et indépendante la cyclogénase-2 dans des échantillons.

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