High level recombinant protein production using conditional...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/86 (2006.01)

Patent

CA 2053187

ABSTRACT OF THE DISCLOSURE The invention relates to a recombinant transfer vector for introducing a DNA sequence encoding a recombinant protein into an adenovirus genome. The transfer vector includes an expression cassette comprising sequentially a transcription promoter, a high efficiency leader, at least one splicing signal, an enhancer-like sequence, a cloning site and a plurality of polyadenylation sites.

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