High molecular weight collagen-like protein polymers

Details High molecular weight collagen-like protein polymers High molecular weight collagen-like protein polymers

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 14/78 (2006.01) C07K 16/44 (2006.01) A61K 38/00 (2006.01) G03C 1/047 (2006.01)

Patent

CA 2123316

2123316 9310154 PCTABS00022 Collagen-like polymers having repetitive triads are produced having reduced proline content, where glycine is the initial amino acid and the subsequent amino acids are varied, while retaining at least a minimum percentage of prolines. The resulting polymers have collagen-like properties, but are capable of being produced in unicellular microorganisms at high molecular weights and in high efficiency. The polymers while retaining collagen-like characteristics, include various novel sequences which impart new characteristics, finding wide use in photographic, medical, structural and fiber applications.

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