High molecular weight meningococcal group c vaccine and...

Details High molecular weight meningococcal group c vaccine and... High molecular weight meningococcal group c vaccine and...

A - Human Necessities

61

K

167/135, 195/140

A61K 39/02 (2006.01) A61K 39/095 (2006.01)

Patent

CA 1112566

ABSTRACT OF THE DISCLOSURE: A vaccine against Group C meningococcal meningitis consisting of a polysaccharide of which at least 80% by weight has a molecular weight in excess of 1,000,000 daltons is prepared. The polysaccharide was isolated from Group C hexadecyl trimethylammonium bromide cell paste with 1.0M CaC12 extraction and purified by phenol extraction, ultra- centrifugation at 100,000 g. and ethanol fractionation (30%-45% v/v in ethanol).

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