High performance cell culture bioreactor and method

Details High performance cell culture bioreactor and method High performance cell culture bioreactor and method

C - Chemistry, Metallurgy

12

M

C12M 3/00 (2006.01)

Patent

CA 2181694

A high performance hollow fiber bioreactor having concentric hollow fiber bundles (22, 23) is disclosed. The central hollow fiber bundle (23) supplies culture medium while the outer hollow filter bundle (22) supplies oxygen needed for cell culture. Methods for use of the high performance bioreactor include, for example, to expand stem cells ex vivo are described.

Un bioréacteur à hautes performances utilise des fibres creuses formées en faisceaux concentriques (22, 23). Le faisceau central (23) de fibres creuses sert à l'alimentation en milieu de culture, alors que le faisceau externe (22) de fibres creuses apporte l'oxygène nécessaire à la culture des cellules. Parmi les utilisations du bioréacteur à hautes performances, on peut citer par exemple la multiplication ex vivo de cellules-souches.

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