High salt binding buffer for immunoglobulin purification...

Details High salt binding buffer for immunoglobulin purification... High salt binding buffer for immunoglobulin purification...

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 1/22 (2006.01)

Patent

CA 2163619

Affinity buffers are disclosed which increase the binding capacity of synthetic affinity chromatographic gels. The buffers of the invention generally comprise aqueous solutions of salts effective to provide a concentration of sulfate, acetate, chloride, potassium, sodium, or ammonium ions sufficient to enhance the binding capacity of such synthetic gels, as shown in the figure.

On décrit des tampons d'affinité qui augmentent la capacité de fixation des gels synthétiques pour chromatographie par affinité. Les tampons de l'invention contiennent généralement des solutions aqueuses de sels capables d'assurer une concentration suffisante en ions sulfate, acétate, chlorure, potassium, sodium ou ammonium pour augmenter la capacité de fixation de ces gels synthétiques, comme représenté sur la figure.

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