G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/64 (2006.01)
Patent
CA 2084742
Apparatus for cross-correlation frequency domain fluorometry and/or phosphorimetry in which means are provided for sequentially performing runs of the cross correlation frequency domain fluorometry and/or phosphorimetry at sequentially differing first and second frequencies, The intensities of signal responses of the runs are detected at the respective cross-correlation frequency in each run. The detection of the signal response is prolonged in each run until an integrated signal with a specified standard deviation has been acquired at each of the differing runs. Preferably the sequential runs are automatically executed by a program. Also, the waveforms sensed by deriving the resultant signal response in each run are folded. That is: corresponding segments of the waveforms are superimposed to obtain an average waveform value for each run having an increased signal to noise ratio over the individual waveform segments. Also, preferably, a software-created variable frequency digital filter is used to filter signal responses at the cross-correlation frequency.
Barbieri Beniamino
Gratton Enrico
Finlayson & Singlehurst
I.s.s. (usa) Inc.
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