High speed preparative countercurrent chromatography with a...

Details High speed preparative countercurrent chromatography with a... High speed preparative countercurrent chromatography with a...

B - Operations, Transporting

01

D

165/19

B01D 15/02 (2006.01) B01D 11/04 (2006.01) G01N 30/42 (2006.01)

Patent

CA 1195234

ABSTRACT OF THE DISCLOSURE A horizontal flow-through apparatus for two-phase countercurrent chromatography consisting of a horizontal multi-layer helically coiled column carried on a flanged reel which is rotated about its own axis and simultaneously revolved around a stationary central parallel horizontal pipe at the same angular velocity and in the same direction to prevent twisting of its inlet and outlet flow tubes, which extend through the stationary central pipe. The multi-layer array can retain a large volume of the stationary phase against a high flow rate of the mobile phase, enabling the separation of the sample components to be completed in a relatively short period of time.

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