High throughput high performance chromatography system

Details High throughput high performance chromatography system High throughput high performance chromatography system

G - Physics

01

N

G01N 30/46 (2006.01) G01N 30/32 (2006.01) G01N 30/74 (2006.01) G01N 30/34 (2006.01) G01N 30/36 (2006.01)

Patent

CA 2427144

A high throughput high performance chromatography system operating at a high mixing pressure including a plurality of pressurized solvent reservoirs, e.g. pumps, each maintaining an associated solvent at a substantially constant pressure. A plurality of flow control valves are connected downstream or upstream of the reservoirs for controlling the flow rate of the solvent into the respective columns. The number of reservoirs equals the number of solvents. Accordingly, the system reduces the number of pumps required thereby saving money and space. Furthermore, the system increases sample throughput, accelerates method development and minimizes organic waste.

La présente invention concerne un système de chromatographie haute performance haut débit, qui fonctionne à une pression de mélange élevée et comprend plusieurs réservoirs de solvant sous pression, tels que des pompes, chacun d'entre eux maintenant un solvant associé à une pression sensiblement constante. Plusieurs vannes de commande de débit sont connectées en aval ou en amont des réservoirs, afin de commander le débit du solvant dans les colonnes respectives. Le nombre de réservoirs est égal au nombre de solvants. Ce système permet de réduire le nombre de pompes nécessaires, économisant ainsi de l'argent et de l'espace. De plus, ce système permet d'augmenter le débit d'échantillons, d'accélérer le déroulement du procédé et de minimiser les déchets organiques.

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