High throughput screening methods for anti-metastatic compounds

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) A01K 67/033 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2635613

High throughput methods for screening of anti-cancer compounds using Drosophila are described. The methods involve modifying the expression of dCsk and observing the effect of putative anti-cancer candidate compounds on resulting expressed characteristics in the Drosophila. Related animal models and apparatus are also provided.

La présente invention concerne des procédés à haut débit qui permettent de cribler des composés anti-cancéreux en utilisant des drosophiles. Les procédés consistent à modifier l'expression de dCsk et à observer l'effet de composés candidats putatifs anti-cancéreux sur les caractéristiques résultantes exprimées chez les drosophiles. L'invention concerne également des modèles animaliers et un dispositif associés.

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