C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) A61K 48/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C12M 1/00 (2006.01) C12N 15/85 (2006.01) C12P 19/34 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2526691
The present invention includes composition and methods for making and using a combinatorial library to identify thioaptamers that bind to targets on or about pathogens. Compositions, kits and methods are also provided for the identification of pathogens, e.g., viral, bacterial or other proteins related infectious disease, as well as, vaccines and vaccine adjuvants are provided that modify host immune responses.
La présente invention concerne une composition et des procédés de fabrication et d'utilisation d'une échantillothèque combinatoire permettant d'identifier des tioaptamères se liant à des cibles sur ou autour de pathogènes. L'invention concerne également des compositions, des nécessaires et des procédés permettant l'identification de pathogènes tels que des maladies infectieuses virales, bactériennes ou en relation avec des protéines. L'invention concerne aussi des vaccins et des adjuvants de vaccins modifiant les réponses immunitaires des hôtes.
Barrett Allan
Bassett Suzanne
Gorenstein David G.
Holbrook Michael
Luxon Bruce A.
Board Of Regents - The University Of Texas System
Shapiro Cohen
LandOfFree
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