High titer varicella zoster immune globulin for intravenous...

Details High titer varicella zoster immune globulin for intravenous... High titer varicella zoster immune globulin for intravenous...

A - Human Necessities

61

K

167/140

A61K 39/395 (2006.01) C07K 16/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1321143

Inventors: MILTON B. DOBKIN Invention: HIGH TITER VARICELLA-ZOSTER IMMUNE GLOBULIN FOR INTRAVENOUS ADMINISTRATION Abstract of the Disclosure Normal plasma from donors who have not been vaccinated with a varicella-zoster vaccine can be screened for higher than normal titers of naturally occurring antibody to varicella- zoster virus. Those plasmas with high titers of such antibody can be pooled and fractionated to give hyperimmune globulin. The product may be treated to render it suitable for intravenous injection. Patients with varicella-zoster infection or at risk to such infection, may receive the present product to raise serum titers of varicella-zoster antibody.

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