A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/713 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01) A61K 47/36 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2685522
Anti-angiogenesis compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions include MAAC solutions or particles present in a therapeutically effective amount, a viscosity-inducing component, and an aqueous carrier component. The compositions have viscosities at about 250C. of at least about 10 cps or about 100 cps at a shear rate of 0. I/second. In a preferred embodiment, the viscosity at 25°C. is in the range of from about 80,000 cps to about 300,000 cps.
L'invention propose des compositions anti-angiogenèse et des procédés d'utilisation de telles compositions qui s'utilisent pour une injection dans l'humeur vitreuses des yeux humains. De telles compositions comprennent des solutions ou des particules de MAAC présentes en une quantité thérapeutique efficace, un composant d'induction de viscosité, et un composant de support aqueux. Les compositions ont des viscosités à environ 250°C d'au moins environ 10 cps ou environ 100 cps à un taux de cisaillement de 0. I/seconde. Dans un mode de réalisation préféré, la viscosité à 25°C se situe dans la plage d'environ 80 000 cps à environ 300 000 cps.
Devries Gerald W.
Hughes Patrick M.
Lyons Robert T.
Trogden John T.
Whitcup Scott M.
Allergan Inc.
Gowling Lafleur Henderson Llp
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