Higher order structure and binding of peptide nucleic acids

Details Higher order structure and binding of peptide nucleic acids Higher order structure and binding of peptide nucleic acids

C - Chemistry, Metallurgy

07

K

C07K 2/00 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/00 (2006.01) C08L 77/00 (2006.01) C08L 81/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2166461

Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.

On utilise les acides nucléiques peptidiques et leurs analogues pour former des structures bicaténaires, tricaténaires et autres avec des acides nucléiques, et pour modifier les acides nucléiques. En outre, on utilise les acides nucléiques peptidiques et leurs analogues pour moduler l'activité des protéines, par exemple par arrêt de la transcription, par initiation de la transcription, et par clivage d'acides nucléiques à des sites spécifiques.

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