C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 38/10 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) C07K 7/08 (2006.01) C07K 14/36 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2720173
The invention refers to so-called Labyrinthopeptin derivatives of the formula (I) wherein {A}, {B}, {C}, R1-R6, m and n are as defined herein, obtainable from microorganism strain Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, a pharmaceutical composition comprising it, prepro-Labyrinthopeptin, pro-Labyrinthopeptin, and DNA coding for prepro-Labyrinthopeptin and pro- Labyrinthopeptin.
L'invention porte sur des dérivés dits de Labyrinthopeptine représentés par la formule (I) dans laquelle {A}, {B}, {C}, R1-R6, m et n sont tels que définis présentement, pouvant être obtenus à partir de la souche de micro-organisme Actinomadura namibiensis (DSM 6313), sur leur utilisation pour le traitement d'infections bactériennes, d'infections virales et/ou de la douleur, sur une composition pharmaceutique les comprenant, sur une prépro-Labyrinthopeptine, sur une pro-Labyrinthopeptine et sur un ADN codant pour la prépro-Labyrinthopeptine et la pro-Labyrinthopeptine.
Broenstrup Mark
Guehring Hans
Hoffmann Holger
Schmiederer Timo
Suessmuth Roderich
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
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