Highly concentrated tcf pharmaceutical preparations

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/19 (2006.01) A61K 38/18 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/16 (2006.01) A61K 47/18 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2116192

This invention provides pharmaceutical preparations containing highly concentrated tumor cytotoxic factor (TCF). The pharmaceutical prparations of the present invention contain highly concentrated TCF and a basic amino acid or their salts, or an organic or inorganic salt as a solubizer. The resultant compositions described in the present invention dissolve TCF at high concentrations of 10 mg/ml or over under about neutral and isotonic conditions. The resultant compositions are stable and are suitable for injection preparations.

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