Highly pure acarbose

Details Highly pure acarbose Highly pure acarbose

C - Chemistry, Metallurgy

07

H

167/199, 260/230

C07H 5/06 (2006.01) A61K 31/70 (2006.01) C07H 15/22 (2006.01)

Patent

CA 1288768

ABSTRACT OF THE DISCLOSURE A purified acarbose which contains less than 10% by weight of sugar-like secondary components is obtained by column chromatography of a solution of prepurified acarbose. The pH of the solution is of 4 to 7. The column contains as a packing material a weakly acidic cation exchanger which has carboxyl groups. The exchanger is based on dextran, agarose or cellulose or on materials derived from these components after the addition of a polyamide.

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