A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5375 (2006.01) A61P 13/02 (2006.01) A61P 13/10 (2006.01)
Patent
CA 2532330
Methods and compositions for treating humans suffering from, or preventing a human from suffering, a physiological or psychiatric disease, disorder, or a condition wherein inhibiting reuptake of nonpinephrine is a benefit are disclosed. The compositions comprise a compound having a pharmacological selectivity of serotonin (K i)/nonpinephrine (K i) of at least about 5000. Examples of such compounds include reboxetine, and more preferably optically pure (S,S) enantiomer of reboxetine. The methods generally include administration of a therapeutic amount of such compositions. Also disclosed are preparations of a medicament from the composition, and uses of the composition in a manufacture of the medicament to treat a human suffering from, or preventing a human from suffering, a physiological or psychiatric disease, disorder, or condition.
Ahmed Saeeduddin
Birgerson Lars
Cetera Pasquale
Marshall Robert Clyde
Mcarthur Robert
Macrae & Co.
Pharmacia & Upjohn Company
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