Highly sulfated derivatives of k5 polysaccharide and their...

Details Highly sulfated derivatives of k5 polysaccharide and their... Highly sulfated derivatives of k5 polysaccharide and their...

C - Chemistry, Metallurgy

08

B

C08B 37/00 (2006.01) A61K 31/715 (2006.01) A61K 31/737 (2006.01)

Patent

CA 2439337

The purification of the E.coli K5 polysaccharide by treatment with isopropyl alcohol and elimination of lipophilic substances is described. The purified product can be used to prepare, after N-deacetylation, new N,O-sulfated polysaccharides with high degree of sulfation.

L'invention se rapporte à la purification de E.coli K5 polysaccharide par traitement avec de l'alcool isopropyle et par élimination des substances lipophiles. Le produit purifié peut être utilisé dans la préparation, après la N-désacétylation, de nouveaux polysaccharides N,O-sulfaté à un degré élevé de sulfatation.

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