Hindered ester-based biodegradable linkers for...

Details Hindered ester-based biodegradable linkers for... Hindered ester-based biodegradable linkers for...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 9/50 (2006.01) A61K 31/7088 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C08G 65/335 (2006.01) C12N 15/11 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2662978

The invention provides hindered ester-based biodegradable linkers for the delivery of oligonucleotides in vivo, as well as method of making and using the same.

L'invention concerne des segments de liaison biodégradables à base d'ester encombré destinés à distribuer des oligonucléotidesin vivo, ainsi qu'un procédé de mise au point et d'utilisation correspondant.

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