Hippophae rhamnoides compositions for cancer therapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 36/185 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2539534

Methods and compositions for prevention and therapy of cancer using a therapeutically effective amount of an extract of Hippophae rhamnoides (sea buckthorn) leaves, berries, and seeds are provided. Novel uses of these compositions in different stages of cancer therapy are disclosed. Novel compositions comprising Hippophae rhamnoides extracts that preferentially inhibit COX-2 over COX-1 are provided. Compositions comprising therapeutically effective amounts of at least one chemotherapeutic agent in addition to Hippophae rhamnoides are provided.

Cette invention concerne des méthodes et des compositions de prévention et de traitement du cancer utilisant une quantité thérapeutiquement efficace d'un extrait de feuilles, de baies et de graines d'Hippophae rhamnoides (argousier). Cette invention concerne également de nouvelles utilisations de ces compositions à différentes étapes de la thérapie anticancéreuse, ainsi que de nouvelles compositions renfermant des extraits d'Hippophae rhamnoides qui inhibent de préférence COX-2 par rapport à COX-1. Cette invention concerne en outre des compositions renfermant des quantités thérapeutiquement efficaces d'au moins un agent chimiothérapeutique en plus de l'Hippophae rhamnoides.

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