Hirudin derivative

Details Hirudin derivative Hirudin derivative

C - Chemistry, Metallurgy

12

N

167/103.05, 530/

C12N 15/15 (2006.01) A61K 38/58 (2006.01) C07K 14/815 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339104

A hirudin derivative of the amino acid sequence (see fig. I) differing in biological activity from other hirudin derivatives, which is to be attributed to differences in the affinity for thrombin and/or differences in the stability and to high biological activity. Moreover, this hirudin derivative can be obtained very efficiently by genetic engineering preparation in yeasts.

591790

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