C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/199, 167/103
C12P 21/02 (2006.01) A61K 31/715 (2006.01) C07K 14/815 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1299126
5579-50 ABSTRACT OF THE DISCLOSURE The present invention relates to a new content substance found in leeches (Hirudo medicinalis), the derivatives of this abbreviated at the N-terminus and the C-terminus, and the desul- fated derivatives therefrom as well as a process for the produc- tion of these compounds, and their use. These compounds possess thrombin-inhibiting properties and can be used to inhibit clotting in humans and animals, for blood conservation, or as reagents for the analytical determination of thrombin.
497453
Dodt Johannes
Fink Ernst
Fritz Hans
Seemuller Ursula
Novartis Ag
Smart & Biggar
Ucp-Gen-Pharma Ag
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