C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/09 (2006.01) A61K 31/4025 (2006.01) A61P 3/04 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2567513
The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
L'invention concerne de nouveaux composés de formule (I) ou des sels pharmaceutiquement acceptables de ces composés qui possèdent une activité antagoniste ou agoniste inverse des récepteurs de l'histamine H3, ainsi que des procédés de préparation de ces composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques comprenant des composés de formule (I) ainsi que des procédé d'utilisation de ces compositions pour traiter l'obésité, les déficiences cognitives, la narcolepsie ainsi que d'autres maladies liées aux récepteurs de l'histamine H3.
Beavers Lisa Selsam
Gadski Robert Alan
Jesudason Cynthia Darshini
Pickard Richard Todd
Stevens Freddie Craig
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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