A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01)
Patent
CA 2284278
The present invention relates to a novel use of histone and provides a pharmaceutical composition containing histone as an active ingredient to improve the symptoms of progressive, inflammatory and autoimmune arthritis. The pharmaceutical composition of the present invention includes histone, especially histone H1 as an active ingredient, and could include pharmacologically approved carriers if necessary. Histone H1 lowered induction of arthritis and reduced arthritis index more effectively than steroidal dexamethasone and also had a significant preventive effect.
La présente invention porte sur une nouvelle utilisation de l'histone et sur une composition pharmaceutique contenant l'histone qui agit comme ingrédient actif de façon à améliorer les symptômes de l'arthrite évolutive, inflammatoire et auto-immune. La composition pharmaceutique de cette invention comprend l'histone, notamment l'histone H1 agissant comme ingrédient actif, et peut comprendre des excipients pharmacologiquement approuvés, si nécessaire. L'histone H1 diminue l'induction de l'arthrite et réduit l'indice de l'arthrite de manière plus efficace que les médicaments traditionnels, et a également un effet préventif notable.
Bae Insoo
Hong Seung-Suh
Jung Neon-Cheol
Kim Dong-Soo
Lee Hyun-Soo
Goudreau Gage Dubuc
Samyang Genex Corporation
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