C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 259/04 (2006.01) A61K 31/29 (2006.01) A61K 31/38 (2006.01) A61K 31/425 (2006.01) A61K 31/47 (2006.01) C07D 215/36 (2006.01) C07D 277/20 (2006.01) C07D 333/34 (2006.01)
Patent
CA 2573509
This invention relates to hydroxamic acid derivatives having a sulfonamide linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.
La présente invention concerne des dérivés d'acide hydroxamique ayant une liaison sulfonamide, qui sont des inhibiteurs d'histone désacétylase (HDAC), et sont utiles dans la prévention et/ou le traitement de maladies cellulaires proliférantes, par exemple, le cancer, les maladies auto-immunes, allergiques et inflammatoires, les maladies du système nerveux central (SNC) telles que les maladies neurodégénératives, et dans la prévention et/ou le traitement d'une resténose.
Belvedere Sandro
Methot Joey Lee
Miller Thomas A.
Witter David J.
Yan Jiaming
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
LandOfFree
Histone deacetylase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Histone deacetylase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Histone deacetylase inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1431668