C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/56 (2006.01) A61K 31/165 (2006.01) A61K 31/277 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) C07C 233/51 (2006.01) C07C 237/40 (2006.01)
Patent
CA 2511479
The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis.
L'invention concerne la préparation et l'utilisation pharmaceutique de nouveaux dérivés de benzamide, tels que définis dans la spécification de la formule (I), en tant qu'inhibiteurs d'histone désacétylase (HDACI), leurs préparations et des procédés d'utilisation de ces composés ou de leur sel acceptable sur le plan pharmaceutique dans le traitement de maladies à prolifération cellulaire, notamment le cancer et le psoriasis.
Deng Tuo
Hu Weiming
Li Boyu
Li Zhibin
Lu Xian-Ping
Gowling Lafleur Henderson Llp
Shenzhen Chipscreen Biosciences Ltd.
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