Histone deacetylase inhibitors with combined activity on...

Details Histone deacetylase inhibitors with combined activity on... Histone deacetylase inhibitors with combined activity on...

A - Human Necessities

61

K

A61K 31/506 (2006.01) A61K 38/05 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2659070

The present invention is concerned with combinations of a proteasome inhibitor and a histone deacetylase inhibitor with combined activity on class-I and class -IIB histone deacetylases, for inhibiting the growth of tumor cells, useful in the treatment of cancer.

La présente invention concerne des combinaisons d'un inhibiteur du protéasome et d'un inhibiteur de la désacétylase exerçant une activité combinée sur les histone désacétylases de classe I et de classe IIB, qui permettent d'inhiber la croissance des cellules tumorales et sont par conséquent utilisés dans le traitement du cancer.

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