C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
195/1.12, 150/8.
C07H 21/04 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2039449
ABSTRACT OF THE DISCLOSURE There is disclosed a method for the detection of HIV-l envelope sequences by the polymerase chain reaction using inosine-substituted "consensus" primers. The primers, modifications of SK68 and SK69, are highly specific and sensitive and they prevent false-negative results due to variation in the HIV-1 genome. Consensus primers are needed to ensure the detection of most, if not all, variants of HIV-l including American, African and newly emerging strains. The primers are of particular value for HIV polymerase chain reaction testing of dry blood samples providing similar specificity and sensitivity.
Arella Max
Cassol Sharon
O'shaughnessy Michael
Salas Teresa
Arella Max
Cassol Sharon
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health
Mcfadden Fincham
O'shaughnessy Michael
LandOfFree
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