Hiv-1 env fragment fusion protein

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/38 (2006.01) A61K 39/21 (2006.01) A61K 39/42 (2006.01) A61K 47/48 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C07K 19/00 (2006.01) C12N 9/00 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2071858

2071858 9109872 PCTABS00005 Highly conserved polypeptide sequences derived from gp4l and gp 120, preferably from eleven to twenty-one amino acids in length, are joined (for example, via DNA recombinant techniques) to a non-HIV protein or polypeptide sequence comprising an amino-acid sequence not naturally encoded by the HIV genome, thereby forming a fusion protein. Such fusion proteins possess attributes that make them suitable for use in the diagnosis, treatment and prevention of HIV infection.

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