Hiv-1 gp41 fusion peptides for immunomodulation

Details Hiv-1 gp41 fusion peptides for immunomodulation Hiv-1 gp41 fusion peptides for immunomodulation

A - Human Necessities

61

K

A61K 38/00 (2006.01)

Patent

CA 2595414

The present invention provides pharmaceutical compositions and methods for prevention or treatment of autoimmune diseases and other T cell mediated inflammatory diseases and conditions, which comprise as an active ingredient an effective quantity of a peptide derived from HIV gp41 fusion peptide domain or fragments, analogs, homologs and derivatives thereof. The invention further provides novel peptides derived from HIV gp41 fusion peptide domain, useful in the treatment of T cell mediated pathologies.

L'invention concerne des compositions pharmaceutiques et des méthodes de prévention ou de traitement des maladies auto-immunes ou d'autres maladies et affections inflammatoires médiées par les lymphocytes T. Ces compositions pharmaceutiques comprennent, comme principe actif, une quantité efficace d'un peptide dérivé du domaine peptidique de fusion HIV gp41 ou de fragments, d'analogues, d'homologues et de dérivés de ces derniers. L'invention concerne également de nouveaux peptides dérivés du domaine peptidique de fusion HIV gp41 utile dans le traitement de pathologies médiées par les lymphocytes T.

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